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Granuloma inguinale is a sexually transmitted disease. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea, but it occurs on occasion in the United States, typically in the Southeast. Granuloma inguinale is caused by the bacteria Calymmatobacterium granulomatis. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea, but it occurs on occasion in the United States, typically in the Southeast.
Granuloma is a nodular type of inflammatory reaction, and inguinale refers to the inguinal region, which is commonly involved in this infection. The disease is commonly known as donovanosis, after the Donovan Bodies which are a diagnostic sign. Granuloma refers to pathogenic and destructive lesions, and inguinale refers to the inguinal region. Because it commonly infected the inguinal region, it was named inguinale
Lesions occur a few days to 3 months after inoculation in the form of 1 or more indurated papules which gradually break down to form ulcers. The ulceration may spread to the entire genitocrural area if untreated, but systemic disease is very rare. Lesions usually appear on the skin or mucous membranes of the genitals, anus, and groin 2 weeks to 3 months after infection.
Granuloma inguinale (donovanosis) is seen predominantly in adults (it rarely occurs in children) and mainly affects genital skin and mucosa. Infection occurs at other skin and mucosal sites, and hematogenous dissemination to bone also has been described. Granuloma inguinale is a sexually transmitted infection that affects the skin and mucous membranes of the anal and genital areas. Its name is derived from granuloma, a medical term for a mass or growth of granulation tissue, and inguinale , a Latin word that means located in the groin. Granuloma inguinale is suspected in patients from endemic areas with characteristic lesions. Diagnosis is confirmed microscopically by the presence of Donovan bodies (numerous bacilli in the cytoplasm of macrophages shown by Giemsa or Wright's stain) in smears of fluid from scrapings from the edge of lesions.
Granuloma inguinale of the cervix, labia majora, and anus developed after diagnostic endometrial curettage. Treatment with tetracycline and later chloramphenicol had to be stopped because of poor patient compliance. Granuloma inguinale is a chronic infection with frequent relapses caused by a rod-shaped bacterium . It occurs worldwide but is most common in tropical or subtropical countries, where it is associated with poverty and poor hygiene. Granuloma inguinale is caused by the bacteria Calymmatobacterium granulomatis . The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea, but it occurs on occasion in the United States, typically in the Southeast.
Granuloma inguinale is a bacterial disease caused by the organism Calymmatobacterium granulomatis . The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea, but it occurs on occasion in the United States, typically in the Southeast. Granuloma inguinale is a relatively rare disease occurring in people living in tropical and subtropical areas. It occurs more frequently in males. Granuloma Inguinale is transmitted through activity with an infected partner. Women with granuloma inguinale can pass the disease onto their child during birth.
Granuloma inguinale is treated with oral antibiotics . Three weeks of treatment with erythromycin, streptomycin, or tetracycline, or 12 weeks of treatment with ampicillin are standard forms of therapy. Granuloma inguinale usually starts with small red skin lumps on the genitals that turn into red, swollen skin patches. The patches can spread and destroy the skin.
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